After over 45 of hours of research, we are stoked to share with you what we have determined are the 14 best ergonomic mice that money can buy. Keep reading for highlight reels of our top picks!
Computer mice have come a long way over the past 15 years or so. Most people remember a time when the average mouse was wired and featured a trackball on the underside of the crude device.
Partially because of dust and grime that would build up in the trackball socket and primarily due to advances in technology, this inefficient version of the mechanical mouse was largely replaced by products such as the optical mouse, the laser mouse, and the wireless mouse, which feature LED and Bluetooth technology.
Today’s computer mice are more ergonomic than they have ever been. If you’re looking to scrap your outdated mouse, you want to replace it with a high-quality product that best fits your needs and increases your productivity at the computer.
In search of the best ergonomic mouse, our experts scoured the web and compiled our top options. We looked at factors such as comfort, precision, battery life, and durability, while also giving weight to features such as wireless capabilities, DPI switches, and built-in rechargeable batteries.
Trackball vs. Laser vs. Optical: What Is the Best Computer Mouse?
When you’re on the hunt for a new computer mouse, you’ll come across products of all shapes and sizes—everything from a simple, wired, trackball mouse to a vertical, wireless, optical mouse. Naturally, you’ll want to know which type of mouse offers the best performance from a technical perspective. So, of the three most common mouse types—trackball, laser, and optical—which is best?
The answer is—it depends.
It depends entirely on your familiarity with different styles, the surface you’re using, and, of course, your personal preferences. With that said, each mouse has its own advantages and disadvantages:
- Trackball. If it’s featured on the underside of the mouse, a trackball can be troublesome; but the trackball on a modern computer mouse is often featured on top of the device, where the user can control the trackball with his or her fingers. With the exception of high-end products, trackball mice are fairly inexpensive.
- Laser. From a performance standpoint, the laser mouse typically boasts a higher DPI for greater sensitivity and is able to be used on any surface. It is most ideal for users who need their cursors to move at fast speeds. However, it is often more expensive than average trackball or optical mouse.
- Optical. Often the term optical is used interchangeably with both trackball and laser mice; but this mouse uses an LED light and only works on smooth surfaces. With a lower DPI than that of a laser mouse, the optical mouse is most ideal for users who don’t require the highest levels of sensitivity. Once a novelty, today’s optical mouse is very affordable.
Are Vertical Mice Better for Carpal Tunnel?
Vertical mice have grown in popularity in recent years, largely because of the belief that they help alleviate carpal tunnel syndrome and arthritis. But how much of this is true?
Clinical studies have proven that vertical mice indeed reduce stress, straining, and discomfort of the wrists, as they allow users to keep their hands and arms in the classic “handshake” position—a posture which requires significantly less twisting and contorting.
If you really want to help alleviate carpal tunnel, consider a trackball and vertical mouse combination. Not only will your hand and wrist maintain better posture but the trackball will also allow you to keep your arm relatively stationary, limiting movement and, subsequently, fatigue.
With a few ideas as to what kind of mouse you might need, let’s dive right into our top 14 picks. Whether you’re an avid gamer, a graphic designer, or a casual computer user, we’re confident that you’ll find your perfect mouse on our list!
View Our 14 Best Ergonomic Mouse Picks Below
#1
Logitech M570 Wireless Trackball Mouse
The classic trackball makes a return with the Logitech M570 wireless mouse, albeit in a much different form. The trackball is controlled by the user’s thumb. This allows the mouse to stay in place, preventing wrist pain and fatigue. Furthermore, the trackball is removable, making the ball and socket easy to clean and maintain.
A sculpted design provides the user with a comfortable grip, while back and forward buttons offer browsing convenience. Keep in mind that this is a right-handed product. If you’re left-handed, unfortunately, you’re out of luck.
The M570 comes with a unifying receiver, which can be plugged right into your computer’s USB port for a seamless wireless connection. Powered by a single AA battery, this mouse boasts an 18-month battery life, providing uninterrupted power for month and months of use on end.
Bottom Line
Not the most expensive mouse on our list but far from the cheapest, the Logitech M570 is a high-quality, ergonomic mouse offered at a fair price.
With a three-year limited hardware warranty, you can trust that your mouse will perform for years to come. But in the rare event that it doesn’t perform to the desired level, you can easily return your mouse and receive a replacement product.
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#2
Anker Ergonomic Optical USB Wired Vertical Mouse
As we alluded to earlier, operating a computer mouse in the palm-down position puts stress on the wrist and arm. So, if you have carpal tunnel syndrome, arthritis, or even normal wrist pain after hours sat at the computer, this ergonomic mouse from Anker might prove to be a real lifesaver.
Immediately, you’ll notice the mouse’s vertical grip. While this type of mouse has a learning curve, the adjustments you make will do wonders for your health in the long run. As an optical mouse, it features 1,000/1,600 DPI resolution, as well as back and forward buttons that can be utilized for easy browsing.
One of the drawbacks of this mouse is that is isn’t wireless. However, its 4.9ft USB cable offers plenty of slack and won’t soon get in the way of other tasks you need to perform at your desk.
Bottom Line
Particularly as it is designed to help relieve and prevent wrist pains, this mouse is worth every penny of its highly affordable price tag.
Not only does this mouse come with an 18-month warranty but it also comes with lifetime support. If you’re ever having issues with your mouse, you can easily get in touch with the Anker support team to get your solution.
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#3
Evoluent VM4R Wired Vertical Mouse
The Evoluent VM4R is another vertical mouse option for those looking to alleviate wrist pain. The mouse features programmable buttons, which can be set via the Evoluent Mouse Manager application once it has been installed on your computer.
With the VM4R, you can also customize your pointer speed by using the mouse’s toggle—no need to hunt through the preferences tab on your computer. Current pointer speed is indicated on the mouse’s built-in LED light panel.
This mouse boasts excellent comfort, providing a smooth bottom edge that prevents the user’s hand from rubbing against his or her desk surface. Furthermore, it features a redesigned thumb rest that perfects the classic “handshake” grip. As this is a wired mouse, you will need to plug the mouse’s cable into one of your computer’s open USB ports in order to use it.
Bottom Line
If you’re looking a premium computer mouse that includes as many bells and whistles as possible, there are very few mice that are able to compete with the Evoluent VM4R.
It should be noted, however, that this mouse is one of the more costly options on our list. As long as you’re not deterred by its price tag, you’ll enjoy a high-quality, durable mouse that you can rely on for years to come.
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#4
Logitech MX Master 2S Wireless Mouse
While the Logitech Master 2S is not a vertical mouse, it does mimic many of the comforts of one, including a sculpted grip and a large thumb rest.
After installing the Logitech Flow program, your MX Master 2S wireless mouse will be able to transition seamlessly from computer to computer—up to three different systems in total, regardless of brand or model.
A wireless mouse, the MX Master 2S can connect to your system via Bluetooth or via the USB receiver that is included with the product. In lieu of AA or AAA batteries, this mouse features a built-in rechargeable battery that is able to hold its charge for 70 days or longer. A USB charging cable is included with your purchase.
Bottom Line
Although it’s not quite as costly as some of the most expensive options on our list, this mouse isn’t exactly cheap. However, those who are drawn to Logitech Flow and a built-in rechargeable battery will find this mouse to be well worth the going price.
This ergonomic mouse makes the perfect addition to any office setup, and it is available in three stylish colors: gray, light gray, and midnight teal.
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#5
Anker 2.4G Wireless Vertical Mouse
With its 2.4G wireless mouse, Anker offers yet another ergonomic solution for those looking to improve their posture. This vertical mouse possesses a smooth, “handshake” grip for maximum comfort.
Optical tracking with DPI resolutions of 800, 1200, and 1600 provides varied levels of sensitivity, which can be controlled using the mouse’s DPI switch button. Like many popular Anker products, this model also includes back and forward buttons for quick browsing navigation.
With a USB receiver, the mouse is able to connect to your laptop or computer wirelessly. Although not included with the product, 2 AAA batteries power this mouse, which goes into power saving mode after eight minutes of inactivity.
Bottom Line
Although this solution from Anker boasts high-quality materials and features, it is surprisingly affordable, compared to similar computer mice in its class.
Additionally, the mouse even comes with an 18-month, hassle-free warranty. If you’re unhappy with your purchase or receive a product with any manufacturing defects, you can easily return your mouse for a replacement product—or, in some case, your money back.
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#6
Logitech MX Ergo Wireless Trackball Mouse
One of the most unique features of this mouse is its hinge, which lies underneath the trackball and can be used to the tilt the mouse to up to 20 degrees, achieving a semi-vertical position.
With programmable buttons, you can customize your mouse to accommodate your personal preferences and shortcuts. For further personalization, MX Ergo is compatible with Logitech Flow, which allows it to be integrated with two computers simultaneously for a better workflow.
By plugging in the mouse’s USB receiver, you can enjoy a wireless connection that ranges up to 33ft. The mouse also boasts Bluetooth capabilities for even greater convenience.
This product features a built-in rechargeable battery that is capable of holding its charge for up to 70 days or more. A charging cable—included with your mouse—plugs into the head of the device and connects to your computer’s USB port.
Bottom Line
If you’re not sure whether you want to go with a conventional, horizontal mouse or an ergonomic, vertical mouse, you’ll get the best of both worlds with the Logitech MX Ergo.
While this mouse does fall on the more expensive end of the spectrum, its many unique features make it a difficult option to pass up.
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#7
Razer DeathAdder Elite Gaming Mouse
If sensitivity and precision are high on your list of priorities, there are few better options than the DeathAdder Elite gaming mouse from Razer. The DeathAdder’s 5G optical sensor boasts resolution levels of up to 16,000 DPI, allowing you to make swift, accurate cursor movements while barely budging your mouse.
With the Razer DeathAdder, you can also change your resolution level on the fly—or any settings, at that—with the mouse’s programmable buttons, which can be customized through Razor Synapse. This program also allows you to customize your mouse’s RGB lighting to match your own unique flair.
Its tactile scroll wheel offers a rubberized, textured grip that is easier to control than the average scroll wheel. While this may not have nearly as much use in an office environment, it’s a very handy feature for gamers.
Bottom Line
This wired mouse is the number one best-selling product in PC gaming mice on Amazon, and it’s easy to see why. Boasting an incredible 99.4% resolution accuracy rate and many customizable features, the Razer DeathAdder still manages to be very inexpensive.
Additionally, this product is backed by a two-year warranty that protects against any manufacturing defects. Whether you’re a passionate gamer or an office worker, this mouse is a great addition in almost any environment.
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#8
Logitech MX Wireless Vertical Mouse
With yet another mouse on our list, Logitech brings us the MX wireless vertical mouse. Like many of the MX series products, this mouse provides a very comfortable grip—this time with a vertical design that boasts an ideal 57-degree angle.
This mouse is compatible with the Logitech Flow program, which allows you to integrate your mouse with multiple computers (up to three) for a seamless workflow. An optical, precision sensor provides high resolution and sensitivity at 4,000 DPI, reducing hand movement and fatigue.
With four customizable buttons, the mouse can be tweaked to accommodate your personal preferences. The MX wireless mouse connects to your computer in any of three ways: via Bluetooth, the mouse’s USB receiver, or by means of its USB C charging cable, which is included with your purchase.
Bottom Line
If you value a vertical design, an exceptional DPI, and wireless connectivity, the Logitech MX should make your shortlist of mouse options.
While you will pay a little more for this mouse, you’ll receive a world of luxury in return. The mouse’s built-in rechargeable battery alone will save you money otherwise spent on batteries, while offering you greater convenience.
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#9
Microsoft Sculpt Ergonomic Mouse (Black Forbus)
If you’d prefer a product from a highly reputable giant in computer technology, look no further than the Sculpt ergonomic mouse from none other than Microsoft. With an ergonomic, sculpted design, this mouse encourages a natural posture, reducing the strain on hand and wrist muscles.
As for buttons, the Microsoft Sculpt offers plenty of convenience for quick navigation. A back button makes it easy to backtrack as needed, while a four-way scroll button facilitates easy and fluid movement within documents, folders, and browsers. Finally, a one-touch Windows button allows you to bypass a number of clicks and gets you to your main menu quickly.
A pair of AA batteries powers this mouse. By plugging in the mouse’s USB receiver, which is included with the mouse, you’re able to connect your mouse to your computer via wireless technology.
Bottom Line
This little, rounded mouse is a great option for those who have smaller hands or those who suffer from wrist pains.
The Sculpt can be purchased at a fairly reasonable price, making it a great investment for Microsoft users who would prefer to remain loyal to a global, trusted brand.
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#10
Lekvey Ergonomic Wireless Vertical Mouse
Although this vertical mouse may not possess the brand name power of some of the other options on our list, the product packs a similar punch with many of the same high-quality features.
On the side of the mouse, back and forward buttons offer greater navigation options, while a DPI toggle allows you to tweak your mouse’s sensitivity levels on the fly. On the subject of resolution, the Lekvey ergonomic mouse features DPI modes of 800, 1,200, and 1,600.
Plugging the mouse’s 2.4G USB receiver into your computer will allow you to enjoy a seamless wireless connection. The Lekvey mouse is also equipped with a built-in rechargeable battery and includes a USB charging cable.
Bottom Line
If your focus is on getting a vertical mouse that doesn’t break the bank, you’ll love the price point of this ergonomic mouse from Lekvey. Not only is it extremely affordable but it also boasts many features comparable with some of the more popular computer mice available.
Furthermore, this product includes an 18-month warranty that ensures a replacement or refund for any defective product. As a Lekvey customer, you’ll also get access to lifetime customer support!
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#11
J-Tech Digital Wired Vertical Mouse
If you want a product that will turn heads at the office, check out the wired vertical mouse from J-Tech Digital.
Upon first glance, you’ll notice the mouse’s blue LED trim, which gives the product a modern look. If you’d prefer to preserve battery life, you can easily turn the LED lights off using the light switch on the underside of the unit.
DPI modes of 800, 1,200, and 1,600 can be selected using the DPI switch on the bottom of the mouse. Back and forward triggers straddle the mouse’s thumb rest and allow you to navigate your window or internet browser conveniently.
One of the most unique features of this particular mouse is its detachable palm rest, which not only provides a comfortable, anti-sweat rest for the user’s hand but also prevents the entire unit from sliding or skidding.
Bottom Line
From a pricing standpoint, the J-Tech Digital vertical mouse is neither expensive nor inexpensive. Although you won’t be dropping a large sum of money on this product, it is backed with a one-year warranty, which guarantees that your mouse will come without defect—otherwise, you’ll be able to get a replacement product or your money back.
Furthermore, the J-Tech Digital team extends lifetime support to all of its customers, ensuring that you can always get the answers you need from a professional representative.
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#12
Nulaxy Ergonomic Wireless Vertical Mouse
As if its ergonomic, vertical design isn’t already an improvement on the traditional computer mouse design, the Nulaxy wireless mouse features a black, rubber matte finish that offers additional comfort.
Similar to a few of the computer mice we’ve included in our list, the Nulaxy mouse possesses a DPI switch that conveniently allows users to adjust sensitivity levels (800, 1,200, and 1,600 DPI) without having to rummage through the preferences submenus.
In addition to conventional left and right click buttons and a scroll wheel, this mouse includes back and forward buttons. With the help of 2.4G technology and a USB receiver, the mouse boasts a wireless connection that is capable of extending up to 30 feet or more. As for power, the unit requires 2 AAA batteries that, unfortunately, are not included with your purchase.
Bottom Line
With one of the lowest price tags on our list, the Nulaxy vertical mouse is a highly affordable option that refuses to compromise on quality.
Whether you’re looking for an inexpensive solution for your carpal tunnel syndrome or you’re in search of an affordable mouse that boasts multiple DPI options, this product is a more-than-worthy choice.
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#13
VicTsing Ergonomic Wireless Vertical Mouse

The ergonomic wireless mouse from VicTsing features a vertical design with a 54-degree tilt, creating an optimal “handshake” grip for the user.
With its DPI toggle, you can adjust sensitivity settings ranging from 1,000 DPI all the way up to 2,400 DPI. In addition to this switch, the mouse features two large back and forward buttons that can be used to move from page to page with ease.
This mouse from VicTsing includes a USB receiver, which plugs right into your computer for a reliable, 2.4G wireless connection. The receiver can be stored in its slot on the underside of the mouse when not in use.
Not only does the mouse use a built-in rechargeable battery as its source of power but it also features a power saving mode that engages after 10 minutes idle.
Bottom Line
With great versatility and reliability, it’s surprising that the VicTsing ergonomic vertical mouse is as affordable as it is.
If you’re looking to upgrade to a computer mouse that boasts a host of premium features for just a fraction of the expected price, there aren’t too many better options that can beat out this wireless mouse from VicTsing!
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#14
Jelly Comb Wireless Vertical Mouse
If you have smaller-than-average hands or prefer a smaller mouse regardless, this wireless mouse from Jelly Comb may be a potential option to consider. Its vertical design provides a comfortable grip and offers plenty of support for the user’s hand and wrist.
On the top of the mouse, a DPI switch allows you to tweak sensitivity levels as needed, while large back and forward buttons feature directly above the mouse’s thumb rest.
Using 2.4G technology, the Jelly Comb mouse offers a highly reliable wireless connection. Simply plug your USB receiver into your computer and enjoy lag-free connectivity for up to at least 30 feet. A single AA battery powers the unit and using the on/off switch on the underside of the mouse before and after use can help conserve battery life.
Bottom Line
In case you have budget restrictions, you’ll be pleased to know that the Jelly Comb wireless vertical mouse is yet another inexpensive option. Furthermore, the mouse is a relatively risk-free purchase, as it comes with a lifetime warranty that offers a replacement or full refund if you’re not 100% satisfied with your purchase.
Finally, if you like having color options, you’ll love that the Jelly Comb mouse is available in in five different color combinations.
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Take Your Computer Setup to the Next Level!
Whether you’re looking for a new, high-tech toy to show off at work or a solution for your chronic wrist pains, there are a variety of options on our list for you to consider.
Fortunately, computer mice are relatively inexpensive, so you don’t ever have to blow your budget in order to find something you like. We encourage you to trial a few of our picks for best ergonomic mouse and see which ones make the biggest difference!










![J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Endurance, Removable Palm Rest & Thumb Buttons [V628] J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Endurance, Removable Palm Rest & Thumb Buttons [V628]](https://unbreakyourself.com/files/images/i/41qblj0ahcl.jpg)

